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Detection of gentamicin in water and milk using chitosan-ZnS-Au nanocomposite based on surface plasmon resonance imaging sensor
Amir Reza Sadrolhosseini, Seyedeh Mehri Hamidi⁎, Younes Mazhdi
The detection of antibiotics in milk, water, and agricultural products is a topic of interest for health care and environmental protection. Some antibiotics such as oxytetracycline and gentamicin are the prominent contaminants in water and milk. In this study, the chitosan-ZnS and chitosan-ZnS-Au nanocomposites were fabricated using a laser ablation technique. The nanocomposites were covered on the glass substrate as a layer sensor characterized by analytical methods. Consequently, the thickness of layers was in the range of 36.3 to 38.21 nm. The surface plasmon resonance image patterns demonstrated the interaction of the gentamicin and oxytetracycline with nanocomposites. As a result, the sensor is sensitive to detect gentamicin, and the limit of detection, the affinity constant, and response time were about 0.1 ppm, 102.04 a.u., and 268 s respectively.